Tangential Flow Filtration (TFF), also known as crossflow filtration, is used to clarify process fluids like cell culture media and to concentrate and buffer exchange macromolecules such as proteins, viruses, nucleic acids, and nanoparticles. Originally developed for commercial manufacturing, TFF is now popular in research labs for processing larger sample volumes. Sartorius' Vivaflow® cassettes simplify TFF for researchers, offering reusable and single-use formats with a wide selection of membrane materials and MWCOs, suitable for concentrating and buffer exchanging molecules from 0.1 to 5 L feed volumes.